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Donor baby 'a step closer'  
   
Charlie Whitaker  
 
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A couple trying to create a baby designed to help them treat their four-year-old son have undergone IVF treatment in America.

Doctors in a hospital in Chicago have implanted two embryos which have been screened to make sure they match Michelle and Jason Whitaker's son Charlie.

The family had been banned from having the procedure at a UK clinic.

Charlie suffers from a type of rare anaemia which increases his chance of cancer - or perhaps other fatal complications.

He could be cured by a transplant of special cells from the new baby's umbilical cord - as long as the baby's tissue was a near-perfect match.

Few matches

However, under normal conditions, only a small proportion of embryos conceived naturally or created through conventional IVF would be a match.

This would mean that the couple might have to have several further children before one matching Charlie was created.

After fertility treatment, nine embryos were produced, and doctors took a single cell from each at an early stage in development.

Best embryos

Each was tested and only those embryos which matched were considered for implantation.

Three fitted the bill, and the best two were implanted into 30-year-old Michelle.

There is less than a 50/50 chance of it working first time around, even though Michelle is relatively young.

If not, they will have to undergo further IVF treatment.

Charlie's disease affects only 50 children in the UK, and he currently needs blood transfusions every three weeks and painful injections almost daily just to keep him alive.

Even if the new baby is a match, there is only a tiny chance that it will develop Charlie's illness.

Stem cells

The umbilical cord contains a type of primitive cell called a stem cell which could help 'kick start' Charlie's body into producing the red blood cells he needs.

The cells would be infused into him in a similar fashion to a bone marrow transplant.

The Human Fertilisation and Embryology Authority (HFEA), which regulates fertility treatment in the UK, ruled that while it was acceptable to test and select embryos to prevent the birth of a baby with a genetic disease, it was not ethically acceptable to select them in order to help another child.

Julie du Plessis, Education Officer for the campaigning group LIFE, said, "This case has pushed the boundaries of science too far".

"Children should not be created in order to serve the medical needs of older siblings . We are creating an industry where children are made to order, bought and sold."



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QUIZ
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Questions



1:

Why have Michelle & Jason Whitaker gone to America?

To get medical treatment for their son Charlie.
To have IVF treatment that is banned in the UK.
To get treatment for their new baby.
To get blood transfusions for their son Charlie.
You said: To have IVF treatment that is banned in the UK.
Well done! To have IVF treatment that is banned in the UK is the right answer.
The answer is that they want to have IVF treatment that is banned in the UK.
You said : To get medical treatment for their son Charlie.
Sorry, that's not the right answer. The correct answer is to have IVF treatment that is banned in the UK.
You said : To get treatment for their new baby.
Sorry, that's not right. The correct answer is to have IVF treatment that is banned in the UK.
You said : To get blood transfusions for their son Charlie.
Bad luck, that's wrong. The correct answer is to have IVF treatment that is banned in the UK.

2:

What is wrong with Charlie?

He has a kind of anaemia.
He has cancer.
As a baby, he had a damaged umbilical cord.
There is nothing wrong with him.
You said: He has a kind of anaemia.
Well done! Charlie has a kind of anaemia.
Look again at the fourth sentence. Charlie has a kind of anaemia.
You said : He has cancer.
Not quite. Charlie has a kind of anaemia.
You said : As a baby, he had a damaged umbilical cord.
Sorry, the right answer is that he has a kind of anaemia.
You said : There is nothing wrong with him.
Sorry, the right answer is that he has a kind of anaemia.

3:

Which word could be used to describe Charlie's disease?

common
unique
rare
commonplace
You said: rare
Well done, rare is the right answer.
The right answer is that Charlie's disease is rare.
You said: common
Sorry, that's the wrong answer. The right answer is rare.
You said: unique
Sorry, that's the wrong answer. The right answer is rare.
You said: commonplace
Sorry, that's the wrong answer. The right answer is rare.

4:

Why do the Whitakers want to make sure that their new baby is a 'match' with Charlie?

If there is a 'match' then Charlie can be given a transplant of cells from the new baby.
If the baby is a 'match' then it will not have the same disease as Charlie.
Because Charlie needs a bone marrow transplant.
Because Charlie needs to have blood transfusions.
You said: If there is a 'match' then Charlie can be given a transplant of cells from the new baby.
Well done. If there is a 'match' Charlie can be given a transplant of cells.
If there is a 'match' Charlie can be given a transplant of cells from the baby.
You said: If the baby is a 'match' then it will not have the same disease as Charlie.
Sorry that's not right. If there is a 'match' Charlie can be given a transplant of cells.
You said: Because Charlie needs a bone marrow transplant.
Sorry that's not right. If there is a 'match' Charlie can be given a transplant of cells.
You said: Because Charlie needs to have blood transfusions.
Sorry that's not right. If there is a 'match' Charlie can be given a transplant of cells.

5:

Where will the stem cells be taken from if there is a transplant?

the blood
the bone marrow
the skin tissue
the umbilical cord
You said: the umbilical cord
Well done. Stem cells will be taken from the umbilical cord if there is a transplant.
Stem cells will be taken from the umbilical cord if there is a transplant.
You said: the blood
Sorry, that's not right. The right answer is that the stem cells will be taken from the umbilical cord if there is a transplant.
You said: the bone marrow
Sorry, that's not right. The right answer is that the stem cells will be taken from the umbilical cord if there is a transplant.
You said: the skin tissue
Sorry, that's not right. The right answer is that the stem cells will be taken from the umbilical cord if there is a transplant.

6:

What is the punctuation mark used in the words 'Whitaker's son' to show that Mr Whitaker has a son?

a comma
a hyphen
an apostrophe
a semi-colon
You said: an apostrophe
Well done! An apostrophe is the right answer.
The answer is an apostrophe.
You said: a comma
Bad luck. The right answer is an apostrophe.
You said:a hyphen
Bad luck. The right answer is an apostrophe.
You said: a semi-colon
Bad luck. The right answer is an apostrophe.

7:

What kind of word is 'tissue'?

an adjective or describing word
a noun
a pronoun
a verb or doing word
You said: a noun
Well done. The word 'tissue' is a noun.
The word 'tissue' is a noun.
You said: an adjective or describing word
Sorry, that's not correct. The right answer is that 'tissue' is a noun.
You said: a pronoun
Sorry, that's not correct. The right answer is that 'tissue' is a noun.
You said: a verb or doing word
Sorry, that's not correct. The right answer is that 'tissue' is a noun.

8:

What is the name of the punctuation mark used to connect the words in: 'four-year-old son'?

a hyphen
a line
a colon
a semi-colon
You said: a hyphen
Well done. A hypen is the name of the punctuation mark used here.
This punctuation mark is called a hyphen.
You said: a line
Sorry, that's not right. The correct answer is a hyphen.
You said: a colon
Sorry, that's not right. The correct answer is a hyphen.
You said: a semi-colon
Sorry, that's not right. The correct answer is a hyphen.

9:

True or false? The HFEA says that the treatment that the Whitakers are getting is not ethically right.

true
false
You said: true
Well done, true is correct! The HFEA says that the treatment that the Whitakers are getting is 'not ethically acceptable'.
The answer is true. The HFEA says that the treatment is 'not ethically acceptable'.
You said: false
Sorry, the right answer to this question is true. The HFEA says that the treatment is 'not ethically acceptable'.

10:

True or false? Julie du Plessis supports the Whitaker's choice to have this special IVF treatment.

true
false
You said: false
Good choice. The answer is false because Julie du Plessis does not support the Whitaker's choice to have this special IVF treatment.
The answer is false. Julie du Plessis does not agree with this treatment.
You said: true
Sorry, the correct answer is false. Julie du Plessis does not agree with this treatment.

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